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However, when it is in excess, these benefits are overcome by a pro-inflammatory activity, being associated with worse haemodynamic and metabolic profile in patients affected by HFpEF [35, 36]

11 Importantly, structural modifications to GLP-1RAs can prolong their half-life to 5-7 days compared to the 1-5 minute long half-life of endogenous GLP-1

Ensure you're consuming a balanced diet with adequate: Protein to maintain muscle mass and stable energy Complex carbohydrates to prevent blood sugar fluctuations Essential vitamins and minerals through a varied diet rich in fruits and vegetables Adequate hydration , especially if experiencing gastrointestinal side effects If you're concerned about nutritional deficiencies, discuss testing with your healthcare provider before considering supplements

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